Consortium

Partner 1: Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Legnaro (Pd), Italy

www.izsvenezie.com

The Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe) is a public veterinary institute which conducts prevention, control and research activities in three main areas: animal health and welfare, food safety and environmental protection. It is part of a national network that consists of nine other public veterinary institutes, each of which covers a specific national geographical area.

In particular, the IZSVe is involved in:

  • Diagnoses and research on infectious livestock diseases and zoonoses
  • Quality control of foods of animal origin for human consumption
  • Control of animal feed
  • Epidemiological surveillance and monitoring
  • Planning of animal health programs
  • Training of veterinary service personnel
  • Production of biopharmaceuticals

The IZSVe provides technical-scientific support to international, national and local programs of monitoring, treatment and eradication of animal diseases, as well as to emergency, livestock and biosafety management programs. With regard to food products of animal origin, the activities of the IZSVe focus on the prevention of food-related risks and increasing the level of safety and quality of foodstuffs for human and animal consumption.
Internationally, the IZSVe has been appointed as:

  • OIE reference laboratory for avian influenza and Newcastle disease
  • OIE reference laboratory for viral encephalopathy and retinopathy of marine fish
  • OIE reference laboratory for salmonella
  • OIE collaborating centre for epidemiology, training and control of emerging avian diseases
  • OIE collaborating centre for diseases at the animal/human interface
  • FAO reference centre for animal influenza and Newcastle disease
  • FAO reference centre for rabies.

These Centers of excellence are responsible for facing scientific and technical problems associated with the diseases included in the OIE lists, for carrying out research and for work towards the standardization of diagnostic techniques.
IZSVe makes available its expertise for international cooperation projects and training activities in order to contribute to the prevention of transboundary animal diseases and for securing consumers’ health.

The research team

IZSVe team

Calogero Terregino, DVM, PhD (Project Coordinator, WP 4 leader) is head of the Virology laboratory of the Research and Development Department at IZSVe. He coordinates and promotes diagnostic and research activities in the field of animal, mainly poultry, and zoonotic infectious diseases. He is the supervisor of experimental viral infection and pathogenesis studies and vaccine challenges in animal models. He has already acted as principal investigator in several national funded research projects and as scientific collaborator or WP leader in international (EU) research funded projects.

Giovanni Cattoli, DVM, PhD (Previous coordinator, WP 6 leader), is the Director of the Research and Innovation Department at the Istituto Zooprofilattico Sperimentale delle Venezie, which includes the National and OIE/FAO Reference Laboratory for Newcastle Disease and Avian Influenza, the National and OIE Collaborating Centre for Diseases at the Human-Animal Interface, the National and FAO Reference Centre for rabies. His main fields of activity concern research on avian and animal influenza, Newcastle disease, and other avian viral infections. Furthermore, he is involved in research and development programs for the application of rapid and innovative diagnostic methods for infectious diseases, development of new vaccination strategy, pathogenesis and molecular epidemiology of animal and zoonotic pathogens.

For the time being (autumn 2016) Dr. Cattoli works at the Animal Production and Health Section, FAO/IAEA Joint Division, IAEA, as Head of Seibersdorf Laboratories.

International research projects involving the participating scientists and active in 2013 and/or 2014:

  • FP7-PREDEMICS – Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches
  • FP7-FLUPIG – Pathogenesis and transmission of influenza in pigs
  • FP7-ESNIP III – European surveillance network for influenza in pigs
  • Project Consortium – FLURISK – Development of a risk assessment methodological framework for potentially pandemic influenza strains
  • EMIDA Era-Net – “EPI-SEQ – Molecular epidemiology of epizootic diseases using next generation sequencing technology”
  • ANIHWA Era-Net – “NADIV – Co-circulation of avian influenza and velogenic Newcastle disease viruses – impact on pathogenesis, immune response and disease prevention”

Contact scientists

Dr Calogero Terregino, DVM, PhD (Project Coordinator, WP 4 leader) Virology Department
Istituto Zooprofilattico Sperimentale delle Venezie Viale dell’Università
10 – 35020 Legnaro (Padova), Italy
Tel: +39 0498084371
Fax +39 0498084360
E-mail: dsbio.izsve@izsvenezie.it

Dr. Giovanni Cattoli, DVM, PhD (Previous coordinator, WP 6 leader),
Recent position and affiliation: Head of Seibersdorf Laboratories
Animal Production and Health Section,
FAO/IAEA Joint Division, IAEA,
Wagramerstrasse 5,
PO Box 100, A1400 Vienna, Austria
G.Cattoli@iaea.org

Partner 2: Centre d’Etudes et de Recherches Veterinaires et Agrochimiques (CODA-CERVA), Brussels, Belgium

www.coda-cerva.be

The CODA-CERVA (Veterinary and Agrochemical Research Centre) is a Federal scientific research establishment. CODA-CERVA’s core activities consist of scientific reseach, expert advice and efficient provision of services in the following fields of activities:

*Veterinary activities:

  • Epidemic, endemic and emerging transmittable diseases in animals
  • Zoonotic and emerging infectious diseases threatening public health
  • Epidemiology: surveillance, risk analysis, and molecular epidemiology

*Agrochemical activities

  • Contaminants and the quality of the environment in the framework of safe food production

It contributes to a proactive policy in terms of food production safety, animal health and public health, at both the Federal and international levels: it supports the preparation of the Federal Public Service for Public Health, food chain safety and environment and of the Federal Agency for the Safety of the Food Chain (FAFSC).
CODA-CERVA is under the wardship of the Minister of SMCs, Independent workers, Agriculture and Scientific policy, and is administratively connected to the Federal Public Service for Public Health, Food Chain Safety and Environment. More information can be obtained on the website http://www.coda-cerva.be/

The research team

CODA-CERVA team

Bénédicte Lambrecht (Work Package 3 leader), ScLic, PhD, is head of the Avian Virology and Immunology Unit which hosting the National Reference Laboratory for Newcastle Disease and Avian Influenza. She coordinates and promotes diagnostic, monitoring and research activities in the field of poultry and wild birds. She is implicated or in charge of national and international research projects with different sponsoring: internal grants; DG4 National Contractual research; BELPSO; EU-ANIHWA call; private company contracts. 

She is the supervisor of experimental viral and transmission infections, pathogenesis studies in animal models and characterization of immunological responses after different types and schedules of vaccination in poultry. He has already acted as principal investigator in several national funded research projects and as scientific collaborator or WP leader in international (EU) research funded projects.

International research projects involving the participating scientists and active in 2013 and/or 2014:

  • EMIDA Era-Net – “EPI-SEQ – Molecular epidemiology of epizootic diseases using next generation sequencing technology”
  • ANIHWA Era-Net – “NADIV – Co-circulation of avian influenza and velogenic Newcastle disease viruses – impact on pathogenesis, immune response and disease prevention”
  • EUFP7- “EUROWESTNILE – European West Nile R&D collaborative project”
  • BELPSO Interuniversity Attraction Poles P7/45 “BELVIR -Virus – host interplay at the early stages of infection”

Contact scientists

Bénédicte Lambrecht, PhD (WP 3 leader)
Avian Virology & Immunology, CODA-CERVA
99 Groeselenberg -1180 Brussels, Belgium
Tel +3223790559
E-mail: belam@coda-cerva.be

Sylvie Marché, PhD
Tel 003223791319
E-mail: symar@coda-cerva.be

Fabienne Rauw, PhD
Tel +3223791321
E-mail: farau@coda-cerva.be

Thu Giang Nguyen
E-mail: thugiang.nguyen@coda-cerva.be

Thierry van den Berg, Operational Director for the Viral Diseases
Tel: +3223790630
E-mail: thvan@coda-cerva.be

Partner 3: The Kimron Veterinary Institute (KVI) at Bet Dagan, Israel

www.moag.gov.il/agri/English/Ministrys+Units/Veterinary+Services/default.htm

The Kimron Veterinary Institute (KVI) is the diagnostic and research arm of the Veterinary Services of the Ministry of Agriculture of Israel. KVI activity concerns prevention, control and research activities in three main areas: animal health and welfare, food safety and environmental protection. The KVI is associated academically with the Hebrew University of Jerusalem and the Koret School of Veterinary Medicine, which are located on the KVI campus. The main function of KVI is research and development, vaccine control and public health. Some units are recognized as national and International centers of zoonoses. Studies are being performed on various diseases of poultry and farm animals.

The research team

KVI team

Irit Davidson (Work Package 2 leader) PhD, is Head of the Unit of Avian Virology Research that focus on avian oncogenic and immunosuppressive viruses, including MDV, retroviruses, CAV, ILTV, FPV, flaviviruses and AIV H9N2. Her fields of activity concerns research on multiple virus infections, including 2 DNA viruses, MDV and FPV and retroviruses resulting in molecular recombination, development of multiplex molecular detection assays and study of feathers as a source of avian viruses for diagnosis and research. On the Institutional level, she serves as the Head of the KVI Scientific Committee and on the National level; ID is active on additional Scientific Committees.

Ruth Haddas (Work Package 2 co-researcher), DVM. Coordinates and promotes diagnostic and research activities in the field of NDV.

International research projects involving the participating scientists and active in 2013 and/or 2014

BARD US-4379-11 Cartography of H9 Avian Influenza Virus and its application to vaccine selection
FP7-ESNIP III – European surveillance network for influenza in pigs

ANIHWA Era-Net – “NADIV – Co-circulation of avian influenza and velogenic Newcastle disease viruses – impact on pathogenesis, immune response and disease prevention”

NADIR FP7 – 228394 The Network of Animal Disease Infectiology and Research Facilities

Contact scientists

Irit Davidson, PhD (WP 2 leader)
Division of Avian Diseases
Kimron Veterinary Institute
Bet Dagan, P.O.Box 12
Israel 50250
Tel. +972-3-9681602
Fax: +972-3-9688964
E-mail: davidsoni@int.gov.il

Ruth Haddas, DVM, Division of Avian Diseases
Kimron Veterinary Institute
Bet Dagan, P.O.Box 12
Israel 50250
Tel. +972-3-9681691
Fax:+972-3-9688964
E-mail: ruth@moag.gov.il

Partner 4: The National Veterinary Institute (Statens Veterinärmedicinska Anstalt, SVA), Uppsala, Sweden

www.sva.se

The National Veterinary Institute (Statens Veterinärmedicinska Anstalt, SVA) is the main centre in Sweden with the overall responsibility for diagnostic and prophylactic work, as well as research and development in infectious diseases of domestic and wild animals. The aim of the activities is to promote animal health and welfare and to minimize hazards associated with animals important to public health and the environment. Under the supervision of the Ministry of Agriculture, SVA plays a central role in the country both in diagnostic services and also as main partner of eradication programs of infectious diseases. SVA is the World Organization for Animal Health (OIE, www.oie.int) Collaborating Centre for Biotechnology-based Diagnosis of Infectious Diseases in Veterinary Medicine with activities focused on development, standardization, validation and dissemination of new molecular diagnostic assays, international standardization, validation, national and international training.

Consortium, main activities

Main lines of activities are: 1) Development of molecular assays for the improved laboratory and on site detection of viral pathogens; 2) Applied and fundamental research on pathogenesis of viral infections; 3) Vaccine constructs, DIVA. The group has expertise relevant for this task in the development of molecular diagnostics, detection of unknown viruses, sequencing and molecular phylogeny, experience in international research through participation in EU projects: Projects FAIR-CT95-707, FAIR-CT95-0316, FAIR-CT98-4123 (coordinator) and QLK2CT-2000- 00486 (coordinator) focused on molecular virology, epizootiology and molecular diagnosis. The group has participated recently in EU projects: CSF VACCINE&WILD BOAR, LAB-ON-SITE (coordinator), PATHOGEN COMBAT, AsemDialog, MED-VET-NET, EPIZONE, FLUTEST, ASFRISK, CSFVgoDIVA, AniBioThreat. Recently the group work in further EU projects, such as RAPIDIA-FIELD, LINK-TADs, EPI-SEQ, among others.

The research team

SVA team

Prof. Sándor Belák, DVM, PhD, DSc, has 40 years’ experience in virology, expert of OIE, FAO, IAEA, director of the OIE Collaborating Centre for the Application of Biotechnology-based Diagnosis of Viral Diseases in Veterinary Medicine, member of European Platform for Global Animal Health, president of the European Society for Veterinary Virology (ESVV) between 2006 and 2012. The author of the chapters in OIE Manual: “Validation and Quality Control of the Polymerase Chain Reaction Methods used for Diagnosis of Infectious Diseases”. Coordinated EU projects FAIR-CT98-4123, QLK2CT-2000-00486 and LAB-ON- SITE (SSP3-513 645).

Dr. Mikael Leijon, PhD, has more than 20 years’ experience in studies of molecular interactions and infectious disease diagnostics. He has served as the research director of LightUp Technologies Inc, a biotech company that specialize in the development of assays for precise viral load quantifications with applications in the field of human infectious disease control. As a researcher at SVA he is developing new diagnostic methods for detection, characterization and pathotyping of AIV, NDV, among others. Recently he was involved in the EU projects FLUTEST and AnioBioThreat.

Contact scientists

Prof. Sándor Belák, DVM, PhD, DSc (WP 5 leader, website manager)
The National Veterinary Institute
The Swedish University of Agricultural Sciences
Ulls väg 2B, SE-751 89 Uppsala, Sweden
Tel: +46 70 552 15 54
E-mail: sandor.belak@slu.se

Mikael Leijon, PhD (WP 1 leader)
The National Veterinary Institute Ulls väg 2B, SE-751 89 Uppsala, Sweden
Tel: +46 18-67 43 17
E-mail: mikael.leijon@sva.se